Parkinson's disease is the second most common neurodegenerative disease in the world, estimated to affect over 6 million people.

Parkinson's disease is caused by the death of dopaminergic neurons in the substantia nigra region of the brain, resulting in both motor and non-motor impairments.

The motor dysfunctions include symptoms such as :

• tremor,
• bradykinesia,
• rigidity,
• impaired balance,
• impaired walking skills.

Non-motor manifestations are characterised by :

• by psychiatric disorders,
• dementia,
• cognitive impairment,
• sleep disturbances,
• pain syndrome.

Treatment of Parkinson's disease symptoms.

The treatment of Parkinson's disease symptoms is based on pharmacological and non-pharmacological options. While pharmacotherapy may only halt the development of symptoms, it is important to note that there are still effective treatment options available. It is true that after a few years, the susceptibility to drug treatment may decrease, leading to complications and reduced quality of life for patients. However, with the right care and management, patients can still lead fulfilling lives.

Advanced techniques such as deep brain stimulation and focused ultrasound guided by magnetic resonance imaging can achieve the reduction of tremors in Parkinson's disease, as well as other movement disorder symptoms. These methods are highly specialised and require qualified professionals and specialised equipment, which limits their availability to select medical centres globally.

Opportunities for the treatment of tremor in Parkinson's disease in Russia

The specialised department of neurodegenerative diseases at the Federal Brain and Neurotechnology Centre of the Federal Medical and Biological Agency of the Russian Federation offers patients exclusive access to state-of-the-art technologies for the diagnosis and treatment of Parkinson's disease. These include deep brain stimulation and focused ultrasound, which are precisely controlled by magnetic resonance imaging. Our medical institution is the only one in Russia that provides these advanced technologies.

Deep brain stimulation (DBS) implants electrodes into the thalamus of the brain and applies electrical impulses to specific areas responsible for motor disorders. This method effectively suppresses tremors and maintains motor function stability.

Magnetic resonance-guided focused ultrasound (MRgFUS) is a non-invasive method of tissue destruction that uses magnetic resonance imaging to establish an area where high-frequency ultrasound is delivered. This technique has been shown to be highly effective in targeted tissue destruction. Magnetic resonance-guided focused ultrasound (MRgFUS) is a non-invasive method of tissue destruction that uses magnetic resonance imaging to establish an area where high-frequency ultrasound is delivered. High-power ultrasound causes thermocoagulation necrosis of cells, resulting in irreversible tissue ablation. This non-surgical procedure allows for precise targeting of deep brain tissue and differentiation, leading to immediate therapeutic effects and a rapid return to normal motor function.

Our highly qualified specialists perform a thorough screening to assess the patient's condition and choose the best therapy option to minimize health risks and maximize positive effects.

We offer assistance in organizing treatment in Russia, with our specialists accompanying patients throughout their stay in the country.